ADAR antibody (AA 200-250)

Catalog No. ABIN7453418

The Rabbit Polyclonal anti-ADAR antibody has been validated for WB, IP and IHC (fp). It is suitable to detect ADAR in samples from Human.

Quick Overview for ADAR antibody (AA 200-250) (ABIN7453418)

Target: ADAR (Adenosine Deaminase, RNA-Specific (ADAR))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADAR antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-ADAR Antibody

Binding Specificity: AA 200-250

Purpose: Rabbit anti-ADAR1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 200 and 250

Isotype: IgG

Application Details

Application Notes:

IHC: 1:1,000 - 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for ADAR

Target: ADAR (Adenosine Deaminase, RNA-Specific (ADAR))

Alternative Name: ADAR1

Background: Background: ADAR1 (adenosine deaminase, RNA specific) is an enzyme responsible for RNA editing by site-specific deamination of adenosines. This enzyme destabilizes double-stranded RNA through conversion of adenosine to inosine. Mutations in this gene have been associated with dyschromatosis symmetrica hereditary [taken from NCBI Entrez Gene (Gene ID: 103)].

Gene ID: 103

NCBI Accession: NP_001102

UniProt: P55265

Pathways: Protein targeting to Nucleus