DCK antibody (AA 210-260)

Catalog No. ABIN7453430

The Rabbit Polyclonal anti-DCK antibody has been validated for WB, IP and IHC (fp). It is suitable to detect DCK in samples from Human and Mouse.

Quick Overview for DCK antibody (AA 210-260) (ABIN7453430)

Target: DCK (Deoxycytidine Kinase (DCK))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DCK antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-DCK Antibody

Binding Specificity: AA 210-260

Purpose: Rabbit anti-DCK Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 210 and 260

Isotype: IgG

Application Details

Application Notes:

IHC: 1:1,000 - 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for DCK

Target: DCK (Deoxycytidine Kinase (DCK))

Alternative Name: DCK

Background: Background: Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivitiy [taken from NCBI Entrez Gene (Gene ID: 1633)].

Gene ID: 1633

NCBI Accession: NP_000779

UniProt: P27707