WDFY3 antibody (AA 500-550)

Catalog No. ABIN7453488

This anti-WDFY3 antibody is a Rabbit Polyclonal antibody detecting WDFY3 in WB, IP and IHC (fp). Suitable for Human.

Quick Overview for WDFY3 antibody (AA 500-550) (ABIN7453488)

Target: WDFY3 (WD Repeat and FYVE Domain Containing 3 (WDFY3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WDFY3 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-WDFY3 Antibody

Binding Specificity: AA 500-550

Purpose: Rabbit anti-WDFY3 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 500 and 550

Isotype: IgG

Application Details

Application Notes:

IHC: 1:1,000 - 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for WDFY3

Target: WDFY3 (WD Repeat and FYVE Domain Containing 3 (WDFY3))

Alternative Name: WDFY3

Background: Background: WDFY3 (WD repeat and FYVE domain -containing protein 3) was identified in a screen for phosphatidylinositol -3-phosphate [PtdIns(3)P]- binding proteins. The FYVE domain is a zinc binding domain found in many PtdIns(3)-binding proteins and is proposed to target proteins to membrane lipids. WDFY3 has been shown localized to the nuclear membrane and within autophagic membranes and it is proposed to function as a link between protein aggregates and the autophagic machinery.

Gene ID: 23001

NCBI Accession: NP_055806

UniProt: Q8IZQ1