RABGEF1 antibody (AA 475-525)

Catalog No. ABIN7453519

This Rabbit Polyclonal antibody specifically detects RABGEF1 in WB, IP and IHC (fp). It exhibits reactivity toward Human.

Quick Overview for RABGEF1 antibody (AA 475-525) (ABIN7453519)

Target: RABGEF1 (RAB Guanine Nucleotide Exchange Factor (GEF) 1 (RABGEF1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RABGEF1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-RABGEF1 Antibody

Binding Specificity: AA 475-525

Purpose: Rabbit anti-RABGEF1 Antibody, Affinity Purified

Predicted Reactivity: Mouse,Bovine

Purification: Affinity Purified

Immunogen: between AA 475 and 525

Isotype: IgG

Application Details

Application Notes:

IHC: 1:1,000 - 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: Not recommended

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for RABGEF1

Target: RABGEF1 (RAB Guanine Nucleotide Exchange Factor (GEF) 1 (RABGEF1))

Alternative Name: RABGEF1

Background: Background: RabGEF1 (Rab guanine nucleotide exchange factor 1) is a rab effector protein acting as linker between gamma-adaptin, Rab4A or Rab5A. RabGEF1 is involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. It stimulates nucleotide exchange on Rab5A. RabGEF1 can act as a ubiquitin ligase [taken from the Universal Protein Resource (UniProt) Q9UJ41].

Gene ID: 27342

UniProt: Q9UJ41

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process