Interleukin enhancer-binding factor 3 (ILF3) (AA 1-50) antibody

Catalog No. ABIN7453538

The Rabbit Polyclonal anti- antibody has been validated for WB and IHC (fp). It is suitable to detect in samples from Human and Mouse.

Quick Overview for Interleukin enhancer-binding factor 3 (ILF3) (AA 1-50) antibody (ABIN7453538)

Target: Interleukin enhancer-binding factor 3 (ILF3)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details

Binding Specificity: AA 1-50

Purpose: Rabbit anti-NF90/NF110 Antibody, Affinity Purified

Predicted Reactivity: Rat

Purification: Affinity Purified

Immunogen: between AA 1 and 50

Isotype: IgG

Application Details

Application Notes:

IHC: 1:1,000 - 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: Not recommended

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details

Target: Interleukin enhancer-binding factor 3 (ILF3)

Alternative Name: NF90/NF110

Background: Background: NFAR (nuclear factor associated with dsRNA) exists as two major protein species of 90 kDa (NFAR-1 or NF90) and 110 kDa (NFAR-2 or NF110) in the cell. NF90 and NF110 arise from a single gene named interleukin enhancer binding factor (ILF3) gene which resides on chromosome 19p13 and are generated through alternative splicing events. NF90 is a dsRNA binding protein that stabilizes mRNAs and regulates transcription. NF90 is a subunit of the nuclear factor of activated T-cells (NFAT) transcription factor that is required for T-cell expression of interleukin 2. The NF110 isoform is restricted to the nucleus and its function may be unrelated to NF90.

Gene ID: 3609

NCBI Accession: NP_036350

UniProt: Q12906

Pathways: M Phase