GTF3C4 antibody (AA 625-675)

Catalog No. ABIN7453562

The Rabbit Polyclonal anti-GTF3C4 antibody has been validated for WB, IP and IHC (fp). It is suitable to detect GTF3C4 in samples from Human.

Quick Overview for GTF3C4 antibody (AA 625-675) (ABIN7453562)

Target: GTF3C4 (General Transcription Factor IIIC, Polypeptide 4 (GTF3C4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GTF3C4 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-GTF3C4 Antibody

Binding Specificity: AA 625-675

Purpose: Rabbit anti-GTF3C4/TFIIIC90 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 625 and 675

Isotype: IgG

Application Details

Application Notes:

IHC: 1:1,000 - 1:5,000. Epitope retrieval with Tris-EDTA pH 9.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: Not recommended. Use rabbit anti-GTF3C4/TFIIIC90 antibody ABIN7453712.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for GTF3C4

Target: GTF3C4 (General Transcription Factor IIIC, Polypeptide 4 (GTF3C4))

Alternative Name: GTF3C4/TFIIIC90

Background: Background: General transcription factor 3C polypeptide 4 (GTF3C4/TFIIIC90) is a subunit of the TFIIIC DNA-binding factor required for transcription of tRNA and 5S rRNA genes by RNA polymerase III. Human TFIIIC is composed of six subunits: TFIIIC220, TFIIIC110, TFIIIC102, TFIIIC90 and TFIIIC63, and TFIIIC35. GTF3C4/TFIIIC90 is required for RNA polymerase III transcription and interacts with TFIIIC220, TFIIIC110, TFCIIIC63, TFIIIB90, and RPC39. GTF3C4/TFIIIC90 has been shown to possess acetyltransferase activity specific for histone H3.

Gene ID: 9329

NCBI Accession: NP_036336

UniProt: Q9UKN8