SMC3 antibody (C-Term)

Catalog No. ABIN7453572

The Rabbit Polyclonal anti-SMC3 antibody (ABIN7453572) specifically detects SMC3 in WB, IP and IHC (fp). The antibody is reactive with Human and Mouse samples.

Quick Overview for SMC3 antibody (C-Term) (ABIN7453572)

Target: SMC3 (Structural Maintenance of Chromosomes 3 (SMC3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMC3 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-SMC3 Antibody

Binding Specificity: C-Term

Purpose: Rabbit anti-SMC3 Antibody, Affinity Purified

Predicted Reactivity: Bovine,Orangutan

Purification: Affinity Purified

Immunogen: between AA 1175 and C-term

Isotype: IgG

Application Details

Application Notes:

IHC: 1:1,000 to 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:10,000 - 1:25,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for SMC3

Target: SMC3 (Structural Maintenance of Chromosomes 3 (SMC3))

Alternative Name: SMC3

Background: Background: SMC3 (structural maintenance of chromosomes 3) is a component of the cohesin complex which is critical for precise duplication and segregation of chromosomes. SMC3 heterodimerizes with SMC1 and associates with two non-SMC subunits, Rad21/Scc1 and Scc3, to form the cohesin complex.

Gene ID: 9126

NCBI Accession: NP_005436

UniProt: Q9UQE7

Pathways: Stem Cell Maintenance