ARID2 antibody (AA 1785-1835)

Catalog No. ABIN7453593

This anti-ARID2 antibody is a Rabbit Polyclonal antibody detecting ARID2 in WB, IP and IHC (fp). Suitable for Human.

Quick Overview for ARID2 antibody (AA 1785-1835) (ABIN7453593)

Target: ARID2 (AT Rich Interactive Domain 2 (ARID, RFX-Like) (ARID2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARID2 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-ARID2 Antibody

Binding Specificity: AA 1785-1835

Purpose: Rabbit anti-ARID2 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 1785 and 1835

Isotype: IgG

Application Details

Application Notes:

IHC: 1:1,000 to 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 5 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for ARID2

Target: ARID2 (AT Rich Interactive Domain 2 (ARID, RFX-Like) (ARID2))

Alternative Name: ARID2

Background: Background: The SWI/SNF-related, matrix-associated, actin-dependent regulators of chromatin (SMARC), also called BRG1-associated factors (BAFs), have been identified as components of the human SWI/SNF-like chromatin-remodeling protein complexes. SWI/SNF complexes possess ATPase and DNA helicase activity that promotes transcriptional activation of genes normally repressed by chromatin structure. ARID2 (AT-rich interactive domain-containing protein 2) is also known as BAF200 and was purified as a factor that associated with PBAF (hSWI/SNF-B). ARID2 is a noncatalytic subunit that is a member of the ARID (AT-rich interactive domain-containing protein) family of DNA binding proteins. In addition to the ARID domain, ARID2 also contains a C2H2-type zinc finger and has been implicated as a transcriptional co-activator for serum response factor for the regulation of cardiac genes.

Gene ID: 196528

NCBI Accession: NP_689854

UniProt: Q68CP9