Dynamitin antibody (AA 351-401)

Catalog No. ABIN7453628

The Rabbit Polyclonal anti-Dynamitin antibody has been validated for WB, IP and IHC (fp). It is suitable to detect Dynamitin in samples from Human.

Quick Overview for Dynamitin antibody (AA 351-401) (ABIN7453628)

Target: Dynamitin (DCTN2) (Dynactin 2 (p50) (DCTN2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Dynamitin antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-Dynamitin Antibody

Binding Specificity: AA 351-401

Purpose: Rabbit anti-DCTN2 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 351 and 401

Isotype: IgG

Application Details

Application Notes:

IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for Dynamitin

Target: Dynamitin (DCTN2) (Dynactin 2 (p50) (DCTN2))

Alternative Name: DCTN2

Background: Background: Dynactin subunit 2 (DCTN2) modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis. DCTN2 is involved in anchoring microtubules to centrosomes. May play a role in synapse formation during brain development [taken from the Universal Protein Resource (UniProt) Q13561].

Gene ID: 10540

NCBI Accession: NP_006391

UniProt: Q13561

Pathways: M Phase, Ribonucleoprotein Complex Subunit Organization