CaMKKa (AA 455-505) antibody
This Rabbit Polyclonal antibody specifically detects CaMKKa in IHC (fp), IP and WB. It exhibits reactivity toward Human.
Catalog No. ABIN7453672
$538.15
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Quick Overview for CaMKKa (AA 455-505) antibody (ABIN7453672)
Target
CaMKKa
Reactivity
Human
Host
Rabbit
Clonality
Polyclonal
Conjugate
Un-conjugated
Application
Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)), Immunoprecipitation (IP), Western Blotting (WB)
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Binding Specificity
- AA 455-505
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Purpose
- Rabbit anti-CaMKK alpha Antibody, Affinity Purified
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Predicted Reactivity
- Mouse,Rat
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Purification
- Affinity Purified
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Immunogen
- between AA 455 and 505
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Isotype
- IgG
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Application Notes
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IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Restrictions
- For Research Use only
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Concentration
- 200 μg/mL
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Buffer
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Expiry Date
- 12 months
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- CaMKKa
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Alternative Name
- CaMKK alpha
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Background
- Background: CaMKK alpha is a calcium/calmodulin-dependent protein kinase that phosphorylates CAMK1, CAMK1D, CAMK1G and CAMK4. CaMKK alpha is involved in regulating cell apoptosis. It promotes cell survival by phosphorylating AKT1/PKB that inhibits pro-apoptotic BAD/Bcl2-antagonist of cell death [taken from the Universal Protein Resource (UniProt) Q8N5S9].
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Gene ID
- 84254
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NCBI Accession
- NP_757343
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UniProt
- Q8N5S9
Target
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