NR1I3 antibody (AA 300-335)

Catalog No. ABIN7460399

The Rabbit Polyclonal anti-NR1I3 antibody is suitable to detect NR1I3 in samples from Human. It has been validated for WB, IP and IHC (fp).

Quick Overview for NR1I3 antibody (AA 300-335) (ABIN7460399)

Target: NR1I3 (Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NR1I3 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-NR1I3 Antibody

Binding Specificity: AA 300-335

Purpose: Rabbit anti-CAR Antibody, Affinity Purified

Predicted Reactivity: Orangutan

Purification: Affinity Purified

Immunogen: between AA 300 and 335

Isotype: IgG

Application Details

Application Notes:

IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for NR1I3

Target: NR1I3 (Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3))

Alternative Name: CAR

Background: Background: Coxsackievirus and adenovirus receptor (CAR) is a component of the epithelial apical junction complex that is essential for the integrity of tight junctions. CAR is proposed to function as a homophilic cell adhesion molecule. It is also thought to be involved in transepithelial migration of polymorphonuclear leukocytes (PMN) through adhesive interactions with AMICA1/JAML located in the plasma membrane of PMN [taken from the Universal Protein Resource (UniProt) P78310].

Gene ID: 1525

NCBI Accession: NP_001329

UniProt: P78310

Pathways: Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway