EHMT1 antibody (AA 25-75)

Catalog No. ABIN7453694

The Rabbit Polyclonal anti-EHMT1 antibody has been validated for WB, IP and IHC (fp). It is suitable to detect EHMT1 in samples from Human.

Quick Overview for EHMT1 antibody (AA 25-75) (ABIN7453694)

Target: EHMT1 (Euchromatic Histone-Lysine N-Methyltransferase 1 (EHMT1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EHMT1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-EHMT1 Antibody

Binding Specificity: AA 25-75

Purpose: Rabbit anti-EHMT1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 25 and 75

Isotype: IgG

Application Details

Application Notes:

IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for EHMT1

Target: EHMT1 (Euchromatic Histone-Lysine N-Methyltransferase 1 (EHMT1))

Alternative Name: EHMT1

Background: Background: Euchromatic histone-lysine N-methyltransferase 1 (EHMT1) is a histone methyltransferase that catalyzes the methylation of lysine-9 of histone H3 (H3-K9). H3-K9 histone methylation is restricted to euchromatin and functions to epigenetically silence gene transcription. Loss of function mutations in EHMT1 cause the 9q34 subtelomeric deletion syndrome, a syndrome characterized by severe mental retardation, hypotonia, brachy(micro)cephaly, heart defects, and distinct facial anomalies.

Gene ID: 79813

NCBI Accession: NP_079033

UniProt: Q9H9B1