DOCK4 antibody (AA 1725-1775)

Catalog No. ABIN7453814

The Rabbit Polyclonal anti-DOCK4 antibody has been validated for WB, IP and IHC (fp). It is suitable to detect DOCK4 in samples from Human.

Quick Overview for DOCK4 antibody (AA 1725-1775) (ABIN7453814)

Target: DOCK4 (Dedicator of Cytokinesis 4 (DOCK4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DOCK4 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-DOCK4 Antibody

Binding Specificity: AA 1725-1775

Purpose: Rabbit anti-DOCK4 Antibody, Affinity Purified

Predicted Reactivity: Mouse

Purification: Affinity Purified

Immunogen: between AA 1725 and 1775

Isotype: IgG

Application Details

Application Notes:

IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 3 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for DOCK4

Target: DOCK4 (Dedicator of Cytokinesis 4 (DOCK4))

Alternative Name: DOCK4

Background: Background: DOCK4 (dedicator of cytokinesis 4) is a member of the CDM gene family and functions as a guanine nucleotide exchange factor (GEF) for the Rac small GTPase. It has been found to play a role in regulating the development of dendrites and rac-dependent cell migration. As a regulator of Rac, DOCK4 participates in wnt signaling by acting as a scaffold and influencing beta-catenin stability.

Gene ID: 9732

NCBI Accession: NP_055520

UniProt: Q8N1I0