STK39 antibody (AA 375-425)

Catalog No. ABIN7453840

This Rabbit Polyclonal antibody specifically detects STK39 in WB, IP and IHC (fp). It exhibits reactivity toward Human.

Quick Overview for STK39 antibody (AA 375-425) (ABIN7453840)

Target: STK39 (serine threonine Kinase 39 (STK39))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STK39 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-STK39 Antibody

Binding Specificity: AA 375-425

Purpose: Rabbit anti-SPAK Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 375 and 425

Isotype: IgG

Application Details

Application Notes:

IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: Not recommended

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for STK39

Target: STK39 (serine threonine Kinase 39 (STK39))

Alternative Name: SPAK

Background: Background: STE20/SPS1-related proline-alanine rich protein kinase (SPAK) is a serine/threonine kinase that is thought to function in the cellular stress response pathway. This kinase is activated in response to hypotonic stress, leading to phosphorylation of several cation-chloride-coupled cotransporters. Catalytically active SPAK specifically activates the p38 MAP kinase pathway, and its interaction with p38 decreases upon cellular stress, suggesting that this kinase may serve as an intermediate in the response to cellular stress [taken from NCBI Entrez Gene (GeneID: 27347)].

Gene ID: 27347

UniProt: Q9UEW8