DDX1 antibody (C-Term)

Catalog No. ABIN7453882

This Rabbit Polyclonal antibody specifically detects DDX1 in WB, IP and IHC (fp). It exhibits reactivity toward Human.

Quick Overview for DDX1 antibody (C-Term) (ABIN7453882)

Target: DDX1 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 1 (DDX1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DDX1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-DDX1 Antibody

Binding Specificity: C-Term

Purpose: Rabbit anti-DDX1 Antibody, Affinity Purified

Predicted Reactivity: Mouse,Rat,Chicken,Bovine

Purification: Affinity Purified

Immunogen: between AA 650 and C-term

Isotype: IgG

Application Details

Application Notes:

IHC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for DDX1

Target: DDX1 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 1 (DDX1))

Alternative Name: DDX1

Background: Background: DDX1 is a member of the DEAD box family of proteins that possesses several conserved motifs which include the highly conserved DEAD (Asp-Glu-Ala-Asp) amino acid sequence motif. The major activity of DEAD box proteins is to function as ATP-dependent RNA helicases. As helicases, DEAD proteins play an important role in all aspects of RNA metabolism and function which include pre-mRNA splicing, RNA synthesis, RNA degradation, RNA export, RNA translation, RNA secondary structure formation, ribosome biogenesis, and the assembly of RNP complexes. DDX1 has been found to associate with factors involved in 3'-end cleavage and polyadenylation of pre-mRNAs.

Gene ID: 1653

UniProt: Q92499

Pathways: Ribonucleoprotein Complex Subunit Organization