Nucleostemin antibody (C-Term)

Catalog No. ABIN7453884

This anti-Nucleostemin antibody is a Rabbit Polyclonal antibody detecting Nucleostemin in WB, IP and IHC (fp). Suitable for Human and Mouse.

Quick Overview for Nucleostemin antibody (C-Term) (ABIN7453884)

Target: Nucleostemin (GNL3) (Guanine Nucleotide Binding Protein-Like 3 (Nucleolar) (GNL3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Nucleostemin antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-Nucleostemin Antibody

Binding Specificity: C-Term

Purpose: Rabbit anti-GNL3 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 500 and C-term

Isotype: IgG

Application Details

Application Notes:

IHC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for Nucleostemin

Target: Nucleostemin (GNL3) (Guanine Nucleotide Binding Protein-Like 3 (Nucleolar) (GNL3))

Alternative Name: GNL3

Background: Background: GNL3 (guanine nucleotide binding protein-like 3), also known as nucleostemin (NS), was identified as a protein highly expressed in stem cells and downregulated in differentiated cells.GNL3 has also been found to be highly expressed in some cancer cell lines, and may play an important role in the control of cell proliferation. GNL3 functions as a GTPase and functions in the processing of nucleolar pre-rRNA.

Gene ID: 26354

NCBI Accession: NP_055181

UniProt: Q9BVP2