WRAP53 antibody (AA 1-50)

Catalog No. ABIN7453892

The Rabbit Polyclonal anti-WRAP53 antibody has been validated for WB, IP and IHC (fp). It is suitable to detect WRAP53 in samples from Human.

Quick Overview for WRAP53 antibody (AA 1-50) (ABIN7453892)

Target: WRAP53 (WD Repeat Containing, Antisense To TP53 (WRAP53))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WRAP53 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-WRAP53 Antibody

Binding Specificity: AA 1-50

Purpose: Rabbit anti-WDR79 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 1 and 50

Isotype: IgG

Application Details

Application Notes:

IHC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for WRAP53

Target: WRAP53 (WD Repeat Containing, Antisense To TP53 (WRAP53))

Alternative Name: WDR79

Background: Background: WD-repeat domain 79 (WDR79) contains six WD (tryptophan-aspartate) repeat domains found in a number of proteins that function as adaptor molecules in signal transduction and cytoskeletal organization. The WD repeat is defined by four or more repeating units of a conserved core of approximately 40 amino acids ending with tryptophan-aspartic acid (WD). WD repeats may serve as sites of protein-protein interaction for adaptor proteins and facilitate multiprotein complex formation. The function of the WDR79 protein has not been characterized, however significant and consistent single nucleotide polymorphisms in the WDR79 gene have been found to be associated with ER negative breast cancer.

Gene ID: 55135

NCBI Accession: NP_060551

UniProt: Q9BUR4

Pathways: Telomere Maintenance