Recombinant Claudin 1 antibody (C-Term)

Catalog No. ABIN7453966

The Rabbit Monoclonal anti-Claudin 1 antibody has been validated for WB, IHC, IP and ICC. It is suitable to detect Claudin 1 in samples from Human.

Quick Overview for Recombinant Claudin 1 antibody (C-Term) (ABIN7453966)

Target: Claudin 1 (CLDN1)

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Claudin 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Clone: BLR094G

Product Details anti-Claudin 1 Antibody

Binding Specificity: C-Term

Purpose: Rabbit anti-Claudin-1 Recombinant Monoclonal Antibody [BLR094G]

Immunogen: between AA 161 and and 211 (C-term)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Borate Buffered Saline (BBS) pH 8.2 with 0.09 % Sodium Azide, BSA-Free

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for Claudin 1

Target: Claudin 1 (CLDN1)

Alternative Name: Claudin-1

Background: Background: Claudins function as major constituents of the tight junction complexes that regulate the permeability of epithelia. While some claudin family members play essential roles in the formation of impermeable barriers, others mediate the permeability to ions and small molecules. Often, several claudin family members are coexpressed and interact with each other, and this determines the overall permeability. Claudin-1 is required to prevent the paracellular diffusion of small molecules through tight junctions in the epidermis and is required for the normal barrier function of the skin. [taken from the Universal Protein Resource (UniProt) O95832].

Gene ID: 9076

NCBI Accession: NP_066924

UniProt: O95832

Pathways: Cell-Cell Junction Organization, Hepatitis C