Recombinant ICOS antibody (AA 149-199)

Catalog No. ABIN7453973

The Rabbit Monoclonal anti-ICOS antibody (Clone BLR194J) (ABIN7453973) specifically detects ICOS in WB, IHC, ICC and IP. The antibody is reactive with Human samples.

Quick Overview for Recombinant ICOS antibody (AA 149-199) (ABIN7453973)

Target: ICOS (Inducible T-Cell Co-Stimulator (ICOS))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This ICOS antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Clone: BLR194J

Product Details anti-ICOS Antibody

Binding Specificity: AA 149-199

Purpose: Rabbit anti-ICOS Recombinant Monoclonal Antibody [BLR194J] - BSA-Free

Purification: Purified

Immunogen: between AA 149 and 199 (C-term)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1000 μg/mL

Buffer: Borate Buffered Saline (BBS) pH 8.2 with 0.09 % Sodium Azide, BSA-Free

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: 2 - 8 °C

Expiry Date: 12 months

Target Details for ICOS

Target: ICOS (Inducible T-Cell Co-Stimulator (ICOS))

Alternative Name: ICOS

Background: ICOS is a member of the CD28 and CTLA-4 cell-surface receptor family. It enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. ICOS is essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9Y6W8].

Gene ID: 29851

UniProt: Q9Y6W8

Pathways: Cancer Immune Checkpoints