Recombinant ZEB2 antibody (AA 1164-1214)

Catalog No. ABIN7453993

The Rabbit Monoclonal anti-ZEB2 antibody has been validated for WB, IHC, IP and ICC. It is suitable to detect ZEB2 in samples from Human.

Quick Overview for Recombinant ZEB2 antibody (AA 1164-1214) (ABIN7453993)

Target: ZEB2 (Zinc Finger E-Box Binding Homeobox 2 (ZEB2))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This ZEB2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Clone: BLR115H

Product Details anti-ZEB2 Antibody

Binding Specificity: AA 1164-1214

Purpose: Rabbit anti-ZEB2/SIP Recombinant Monoclonal Antibody [BLR115H]

Immunogen: between AA 1164 and 1214 (C-term)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Borate Buffered Saline (BBS) pH 8.2 with 0.09 % Sodium Azide, BSA-Free

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for ZEB2

Target: ZEB2 (Zinc Finger E-Box Binding Homeobox 2 (ZEB2))

Alternative Name: ZEB2/SIP

Background: Background: Smad interacting protein 1 (SIP1) is a transcriptional inhibitor that binds to the DNA sequence, 5'-CACCT-3', in different promoters. SIP1 has been shown to repress the transcription of E-cadherin. Defects in the gene which encodes for SIP1, ZEB2, are the cause of Hirschsprung disease-mental retardation syndrome (Hirschsprung disease) also known as Mowat-Wilson syndrome (MWS). Hirschsprung disease is a rare autosomal dominant complex developmental disorder [taken from the Universal Protein Resource (UniProt) O60315].

Gene ID: 9839

NCBI Accession: NP_055610

UniProt: O60315

Pathways: Tube Formation