Recombinant BRD3 antibody (AA 676-726)

Catalog No. ABIN7454022

This Rabbit Monoclonal antibody specifically detects BRD3 in WB, IHC, IP, IF (p) and ICC. It exhibits reactivity toward Human.

Quick Overview for Recombinant BRD3 antibody (AA 676-726) (ABIN7454022)

Target: BRD3 (Bromodomain Containing 3 (BRD3))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This BRD3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC)

Clone: BLR069G

Product Details anti-BRD3 Antibody

Binding Specificity: AA 676-726

Purpose: Rabbit anti-BRD3 Recombinant Monoclonal Antibody [BLR069G]

Immunogen: between AA 676 and 726

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Borate Buffered Saline (BBS) pH 8.2 with 0.09 % Sodium Azide, BSA-Free

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for BRD3

Target: BRD3 (Bromodomain Containing 3 (BRD3))

Alternative Name: BRD3

Background: Background: BRD3 (bromodomain containing 3) is a double bromo-domain containing protein. It has been shown to associate with hyperacetylated chromatin of transcribed genes. From this finding it is suggested that BRD3 plays a role in RNA polymerase II transcription through nucleosomes. A chromosomal translocation resulting in a fusion protein involving BRD3 and NUT has been associated with a rare and lethal carcinoma. [taken from the Universal Protein Resource (UniProt) Q15059 and from NCBI Entrez Gene (Gene ID: 8019)].

Gene ID: 8019

NCBI Accession: NP_031397

UniProt: Q15059

Pathways: Chromatin Binding