Recombinant CD40 antibody (AA 227-277)

Catalog No. ABIN7454023

The Rabbit Monoclonal anti-CD40 antibody has been validated for WB, IHC, IP, ICC and IF (p). It is suitable to detect CD40 in samples from Human.

Quick Overview for Recombinant CD40 antibody (AA 227-277) (ABIN7454023)

Target: CD40

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CD40 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Clone: BLR056F

Product Details anti-CD40 Antibody

Binding Specificity: AA 227-277

Purpose: Rabbit anti-CD40 Recombinant Monoclonal Antibody [BLR056F]

Immunogen: between AA 227 and 277 (C-term)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Borate Buffered Saline (BBS) pH 8.2 with 0.09 % Sodium Azide, BSA-Free

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for CD40

Target: CD40

Alternative Name: CD40

Background: Background: CD40 is a member of the TNF-receptor superfamily. It is a receptor on antigen-presenting cells of the immune system and is essential for mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. [provided by RefSeq, Nov 2014] [taken from NCBI Entrez Gene (Gene ID: 958)].

Gene ID: 958

NCBI Accession: NP_001241

UniProt: P25942

Pathways: NF-kappaB Signaling, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints