APOC1
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Restrictions
For Research Use only
Concentration
1 mg/mL
Buffer
75 mM Sodium Phosphate, 75 mM NaCl, 0.5 mM EDTA, 0.02 % Sodium azide, pH 7.2
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C
Expiry Date
12 months
Target
APOC1
(Apolipoprotein C-I (APOC1))
Alternative Name
ApoCI
Background
Background: ApoCI contains 57 amino acid residues and the m.w. is 6.6 kDa (Jackson et al., 1974). ApoCI has been found to activate LCAT (Liu and Subbaiah 1993). Apo CI is an inhibitor of lipoprotein binding to the LDL receptor, LDL receptor-related protein, and VLDL receptor. Apo CI is also an inhibitor of the plasma cholesteryl ester transfer protein and of fatty acid uptake into tissues (Shachter, 2001). This inhibition role can potentially regulate several lipase enzymes. (Poensgen, 1990, Conde-Knape et al., 2002, Berbee et al., 2005)