APOE antibody (FITC)

Catalog No. ABIN7454060

This anti-APOE antibody is a Goat Polyclonal antibody detecting APOE in . Suitable for Human.

Quick Overview for APOE antibody (FITC) (ABIN7454060)

Target: APOE (Apolipoprotein E (APOE))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This APOE antibody is conjugated to FITC

Application: Please inquire

Clone: F10

Product Details anti-APOE Antibody (FITC)

Purpose: Goat anti-Human Apo E [F10] Antibody FITC Conjugated

Immunogen: Human Apolipoprotein E

Isotype: IgG

Application Details

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: 75 mM Sodium Phosphate, 75 mM NaCl, 0.5 mM EDTA, 0.02 % Sodium azide, pH 7.2

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for APOE

Target: APOE (Apolipoprotein E (APOE))

Alternative Name: ApoE

Background: Background: Apo E contains 299 amino acid residues. It is a 34-37 kDa glycosylated protein (Rall et al., 1983). Apo E is involved with triglyceride, phospholipid, cholesteryl ester, and cholesterol transport in and out of cells and is a ligand for LDL receptors. Apo E has also been implicated in immune and nerve degeneration. It has been found to suppress lymphocyte proliferation. Late-onset familial and sporadic Alzheimer disease patients have been found to have a higher occurrence of one of the three common Apo E isoforms, Apo E4. The Apo E4 isoform has been detected in senile plaques and neurofibrillary tangles of Alzheimer disease patients. Apo E4 is associated with rapid chylomicron-remnant clearance and increased total cholesterol levels.

Gene ID: 348

NCBI Accession: NP_000032

UniProt: P02649

Pathways: Regulation of Cell Size, Lipid Metabolism