PAF1/PD2 antibody (AA 475-525)

Catalog No. ABIN7454365

Product Details anti-PAF1/PD2 Antibody

Target: PAF1/PD2 (PAF1) (Paf1, RNA Polymerase II Associated Factor, Homolog (PAF1))

Binding Specificity: AA 475-525

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAF1/PD2 antibody is un-conjugated

Application: Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Purpose: Rabbit anti-Paf1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 475 and 525

Isotype: IgG

Application Details

Application Notes:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: Not recommended

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for PAF1/PD2

Target: PAF1/PD2 (PAF1) (Paf1, RNA Polymerase II Associated Factor, Homolog (PAF1))

Alternative Name: Paf1 (PAF1 Products)

Background: Background: Paf1 is a component of the Paf1 complex that was originally identified in yeast as an RNA-polymerase II (RNAP II)-associated complex. The Paf1 complex functions in multiple aspects of gene expression. Paf1 has been shown to play roles in transcript elongation, histone H2B monoubiquitination, H3 methylation, chromatin remodeling, mRNA 3'-end processing, and the coupling of transcriptional and posttranscriptional events.

Gene ID: 54623

UniProt: Q8N7H5, Q9NUU9

Pathways: Cellular Response to Molecule of Bacterial Origin, Stem Cell Maintenance