PAF1/PD2 antibody (N-Term)

Catalog No. ABIN2788815

The Rabbit Polyclonal anti-PAF1/PD2 antibody is suitable to detect PAF1/PD2 in samples from Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio). It has been validated for WB and IHC.

Quick Overview for PAF1/PD2 antibody (N-Term) (ABIN2788815)

Target: PAF1/PD2 (PAF1) (Paf1, RNA Polymerase II Associated Factor, Homolog (PAF1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAF1/PD2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-PAF1/PD2 Antibody

Binding Specificity: N-Term

Sequence: IQAPTSSKRS QQHAKVVPWM RKTEYISTEF NRYGISNEKP EVKIGVSVKQ

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against PAF1. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 531 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PAF1/PD2

Target: PAF1/PD2 (PAF1) (Paf1, RNA Polymerase II Associated Factor, Homolog (PAF1))

Alternative Name: PAF1

Background: PAF1, parafibromin, LEO1, and CTR9 form the PAF protein complex that associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. The PAF complex also has a role in histone monoubiquitination.
Alias Symbols: F23149_1, FLJ11123, PD2
Protein Interaction Partner: LEO1, FXR2, CIAO1, MSL1, KAT8, RNF20, MSL2, MSL3, RNF40, UBC, POLR2A, MDM2, HIST1H1C, SUPT16H, NUP98, CHUK, MYH14, ARFGEF2, DNMT3B, DNMT3A, SOX2, MDC1, CDC73, HSPA14, ZC3H4, RTF1, CTR9, XRCC5, SSRP1, CSNK2A2, CSNK2A1, UBE2E1, TCEA1, PTPN11, MLLT1, WDR61,
Protein Size: 531

Molecular Weight: 58 kDa

Gene ID: 54623

NCBI Accession: NM_019088, NP_061961

UniProt: Q8N7H5

Pathways: Cellular Response to Molecule of Bacterial Origin, Stem Cell Maintenance