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PAF1/PD2 Products

(Paf1, RNA Polymerase II Associated Factor, Homolog (PAF1))

Categories

This gene encodes a subunit of the polymerase associated factor (PAF1) complex. The PAF1 complex interacts with RNA polymerase II and plays a role in transcription elongation as well as histone modifications including ubiquitylation and methylation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012].

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Featured PAF1/PD2 Categories

PAF1/PD2 Antibodies

High quality antibodies with extensive validation data.

PAF1/PD2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PAF1/PD2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7168299
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (2)
Cat. No. ABIN1537336
Quantity 400 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7246646
Quantity 200 μL
Datasheet Datasheet

Recommended PAF1/PD2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6231952
Quantity 96 tests
Datasheet Datasheet

Recommended PAF1/PD2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3094414
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3136561
Quantity 1 mg
Datasheet Datasheet
Reactivity Rat
Source Yeast
Validations
Cat. No. ABIN1629621
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our PAF1/PD2 products

Zhi, Giroux-Leprieur, Wislez, Hu, Zhang, Shi, Du, Wang: "Human RNA polymerase II associated factor 1 complex promotes tumorigenesis by activating c-MYC transcription in non-small cell lung cancer." in: Biochemical and biophysical research communications, Vol. 465, Issue 4, pp. 685-90, (2015) (PubMed).

Katsogiannou, Andrieu, Baylot, Baudot, Dusetti, Gayet, Finetti, Garrido, Birnbaum, Bertucci, Brun, Rocchi: "The functional landscape of Hsp27 reveals new cellular processes such as DNA repair and alternative splicing and proposes novel anticancer targets." in: Molecular & cellular proteomics : MCP, Vol. 13, Issue 12, pp. 3585-601, (2014) (PubMed).

Chipumuro, Henriksen: "The ubiquitin hydrolase USP22 contributes to 3'-end processing of JAK-STAT-inducible genes." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 26, Issue 2, pp. 842-54, (2012) (PubMed).

Willmann, Milosevic, Pauklin, Schmitz, Rangam, Simon, Maslen, Skehel, Robert, Heyer, Schiavo, Reina-San-Martin, Petersen-Mahrt: "A role for the RNA pol II-associated PAF complex in AID-induced immune diversification." in: The Journal of experimental medicine, Vol. 209, Issue 11, pp. 2099-111, (2012) (PubMed).

Langenbacher, Nguyen, Cavanaugh, Huang, Lu, Chen: "The PAF1 complex differentially regulates cardiomyocyte specification." in: Developmental biology, Vol. 353, Issue 1, pp. 19-28, (2011) (PubMed).

Panicker, Zhang, Dagur, Gastinger, Simonds: "Defective nucleolar localization and dominant interfering properties of a parafibromin L95P missense mutant causing the hyperparathyroidism-jaw tumor syndrome." in: Endocrine-related cancer, Vol. 17, Issue 2, pp. 513-24, (2010) (PubMed).

Jurynec, Grunwald: "SHIP2, a factor associated with diet-induced obesity and insulin sensitivity, attenuates FGF signaling in vivo." in: Disease models & mechanisms, Vol. 3, Issue 11-12, pp. 733-42, (2010) (PubMed).

Lin, Czapiga, Nini, Zhang, Simonds: "Nuclear localization of the parafibromin tumor suppressor protein implicated in the hyperparathyroidism-jaw tumor syndrome enhances its proapoptotic function." in: Molecular cancer research : MCR, Vol. 5, Issue 2, pp. 183-93, (2007) (PubMed).

Youn, Yoo, Kim, Hwang, Choi, Desiderio, Yoo: "hCTR9, a component of Paf1 complex, participates in the transcription of interleukin 6-responsive genes through regulation of STAT3-DNA interactions." in: The Journal of biological chemistry, Vol. 282, Issue 48, pp. 34727-34, (2007) (PubMed).

Zhu, Mandal, Pham, Zheng, Erdjument-Bromage, Batra, Tempst, Reinberg: "The human PAF complex coordinates transcription with events downstream of RNA synthesis." in: Genes & development, Vol. 19, Issue 14, pp. 1668-73, (2005) (PubMed).

Synonyms and alternative names related to PAF1/PD2

PAF1 homolog, Paf1/RNA polymerase II complex component (PAF1), Paf1, RNA polymerase II complex component (Paf1), PAF1 homolog, Paf1/RNA polymerase II complex component (paf1), PAF1 homolog, Paf1/RNA polymerase II complex component L homeolog (paf1.L), RNA polymerase II-associated factor 1 homolog pseudogene (LOC100019208), RNA polymerase II-associated factor 1 homolog (LOC100161171), paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) (paf1), RNA polymerase II-associated factor 1 homolog (LOC100639019), RNA polymerase II-associated factor 1 homolog (LOC100650306), PAF1 homolog, Paf1/RNA polymerase II complex component (Paf1), Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) (PAF1), 5730511K23Rik, AA675045, F23149_1, f23149_1, im:6906070, paf1, paf1l, PD2, pd2, RGD1306219, wu:fb80a09

Protein level used designations for PAF1/PD2

  • RNA polymerase II-associated factor 1 homolog
  • pancreatic differentiation protein 2
  • PD2-like protein
  • paf1, RNA polymerase II associated factor, homolog, like
  • Paf1, RNA polymerase II associated factor, homolog
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