DCAF6 antibody (AA 300-350)

Catalog No. ABIN7454449

The Rabbit Polyclonal anti-DCAF6 antibody is suitable to detect DCAF6 in samples from Human. It has been validated for IP and IHC (fp).

Quick Overview for DCAF6 antibody (AA 300-350) (ABIN7454449)

Target: DCAF6 (DDB1 and CUL4 Associated Factor 6 (DCAF6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DCAF6 antibody is un-conjugated

Application: Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-DCAF6 Antibody

Binding Specificity: AA 300-350

Purpose: Rabbit anti-NRIP Antibody, Affinity Purified

Predicted Reactivity: Mouse,Orangutan

Purification: Affinity Purified

Immunogen: between AA 300 and 350

Isotype: IgG

Application Details

Application Notes:

IHC: 1:500 to 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: Not recommended. Use rabbit anti-NRIP antibody A302-435A.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for DCAF6

Target: DCAF6 (DDB1 and CUL4 Associated Factor 6 (DCAF6))

Alternative Name: NRIP

Background: Background: Nuclear receptor interaction protein (NRIP) was isolated as a ligand-dependent coactivator of the androgen receptor (AR) and glucocorticoid receptor (GR). NRIP was found to enhance the promoter activity of the AR-driven PSA promoter. NRIP is a target gene for AR and Sp1, and complex formation between AR and NRIP protects AR protein from proteasome degradation.

Gene ID: 55827

NCBI Accession: NP_001017977

UniProt: Q58WW2