BIN1 antibody (AA 300-350)

Catalog No. ABIN7454464

The Rabbit Polyclonal anti-BIN1 antibody has been validated for IP and IHC (fp). It is suitable to detect BIN1 in samples from Human.

Quick Overview for BIN1 antibody (AA 300-350) (ABIN7454464)

Target: BIN1 (Bridging Integrator 1 (BIN1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BIN1 antibody is un-conjugated

Application: Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-BIN1 Antibody

Binding Specificity: AA 300-350

Purpose: Rabbit anti-Bin1 Antibody, Affinity Purified

Predicted Reactivity: Mouse,Rat

Purification: Affinity Purified

Immunogen: between AA 300 and 350

Isotype: IgG

Application Details

Application Notes:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 5 - 15 μg/mg lysate

WB: Not recommended. Use rabbit anti-Bin1 antibody A302-729A.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for BIN1

Target: BIN1 (Bridging Integrator 1 (BIN1))

Alternative Name: Bin1

Background: Background: Bin1 (bridging integrator 1) may be involved in the regulation of synaptic vesicle endocytosis. It may act as a tumor suppressor and inhibits malignant cell transformation. Defects in BIN1 are the cause of centronuclear myopathy autosomal recessive (ARCNM) [taken from the Universal Protein Resource (UniProt) ww.uniprot.org/uniprot/O00499].

Gene ID: 274

NCBI Accession: NP_647593

UniProt: O00499