MYB antibody (AA 225-275)

Catalog No. ABIN7454503

The Rabbit Polyclonal anti-MYB antibody is suitable to detect MYB in samples from Human. It has been validated for IP and IHC (fp).

Quick Overview for MYB antibody (AA 225-275) (ABIN7454503)

Target: MYB (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYB antibody is un-conjugated

Application: Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-MYB Antibody

Binding Specificity: AA 225-275

Purpose: Rabbit anti-c-Myb Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 225 and 275

Isotype: IgG

Application Details

Application Notes:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: Not recommended. Use rabbit anti-c-Myb antibody A304-138A.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for MYB

Target: MYB (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB))

Alternative Name: c-Myb

Background: Background: c-Myb is a member of the MYB family of transcription factors. C-Myb contains three domains, an N-terminal DNA-binding domain, a central transcriptional activation domain and a C-terminal domain involved in transcriptional repression. C-myb plays an essential role in the regulation of hematopoiesis and may play a role in tumorigenesis [taken from NCBI Entrez Gene (Gene ID: 3093)].

Gene ID: 4602

NCBI Accession: NP_005366

UniProt: P10242

Pathways: Chromatin Binding, Positive Regulation of Immune Effector Process