CRABP2 antibody (C-Term)

Catalog No. ABIN7454522

This anti-CRABP2 antibody is a Rabbit Polyclonal antibody detecting CRABP2 in WB and IHC (fp). Suitable for Human.

Quick Overview for CRABP2 antibody (C-Term) (ABIN7454522)

Target: CRABP2 (Cellular Retinoic Acid Binding Protein 2 (CRABP2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CRABP2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-CRABP2 Antibody

Binding Specificity: C-Term

Purpose: Rabbit anti-CRABP2 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 80 and C-term

Isotype: IgG

Application Details

Application Notes:

IHC: 1:200 - 1:1,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: Not recommended. While trace amounts of CRABP2 can be immunoprecipitated by A300-809A, the efficiency is very low.

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for CRABP2

Target: CRABP2 (Cellular Retinoic Acid Binding Protein 2 (CRABP2))

Alternative Name: CRABP2

Background: Background: Cellular retinoic acid binding protein 2 (CRABP2) is a coactivator present in the retinoic acid (RA)-dependent nuclear complex. CRABP2 has been shown to mediate retinoic acid activity in skin to influence skin cell growth and differentiation. It has also been shown to mediate the growth suppressive effects of retinoic acid in breast cancer. CRABP2's role in cell differentiation may be linked to control of the cell-cycle since it has been identified as an interacting partner of cyclin D3 in CRABPII and RAR ternary complex.

Gene ID: 1382

NCBI Accession: NP_001869

UniProt: P29373