TCEA3 antibody (AA 200-250)

Catalog No. ABIN7454550

This Rabbit Polyclonal antibody specifically detects TCEA3 in WB and IHC (fp). It exhibits reactivity toward Human and Mouse.

Quick Overview for TCEA3 antibody (AA 200-250) (ABIN7454550)

Target: TCEA3 (Transcription Elongation Factor A (SII), 3 (TCEA3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TCEA3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-TCEA3 Antibody

Binding Specificity: AA 200-250

Purpose: Rabbit anti-TFIIS Antibody, Affinity Purified

Predicted Reactivity: Rat,Bovine

Purification: Affinity Purified

Immunogen: between AA 200 and 250

Isotype: IgG

Application Details

Application Notes:

IHC: 1:200 - 1:1,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: Not recommended. Use rabbit anti-TFIIS antibody A302-239A.

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for TCEA3

Target: TCEA3 (Transcription Elongation Factor A (SII), 3 (TCEA3))

Alternative Name: TFIIS

Background: Background: Transcription elongation factor S-II protein 2 (TFIIS) is necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus [taken from the Universal Protein Resource (UniProt) Q15560].

Gene ID: 6917

NCBI Accession: NP_006747

UniProt: P23193