SP1 antibody (C-Term)

Catalog No. ABIN7458075

This Rabbit Polyclonal antibody specifically detects SP1 in WB, IP and IHC (fp). It exhibits reactivity toward Human and Mouse.

Quick Overview for SP1 antibody (C-Term) (ABIN7458075)

Target: SP1 (Sp1 Transcription Factor (SP1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-SP1 Antibody

Binding Specificity: C-Term

Purpose: Rabbit anti-Sp1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 750 and C-term

Isotype: IgG

Application Details

Application Notes:

IHC: 1:2,000 - 1:10,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for SP1

Target: SP1 (Sp1 Transcription Factor (SP1))

Alternative Name: Sp1

Background: Background: Specificity protein 1 (Sp1) is the original member of the Sp1-like/KLF family of zinc-finger transcription factors that binds GC-rich DNA elements to regulate transcription of genes involved in a variety of cellular functions. Sp-1 interacts with coactivators such as p300/CBP, TAFII130, and CRSP.

Gene ID: 6667

NCBI Accession: XP_028606

UniProt: P08047

Pathways: Regulation of Lipid Metabolism by PPARalpha, Myometrial Relaxation and Contraction