LSD1 antibody (AA 50-100)
Quick Overview for LSD1 antibody (AA 50-100) (ABIN7454595)
Target
See all LSD1 (KDM1A) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 50-100
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Purpose
- Rabbit anti-BHC110/LSD1 Antibody, Affinity Purified
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Purification
- Affinity Purified
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Immunogen
- between AA 50 and 100
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Isotype
- IgG
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Application Notes
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IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 5 μg/mg lysate
WB: 1:5,000 - 1:15,000
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Restrictions
- For Research Use only
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Concentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Expiry Date
- 12 months
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- LSD1 (KDM1A) (Lysine (K)-Specific Demethylase 1A (KDM1A))
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Alternative Name
- BHC110/LSD1
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Background
- Background: BHC110/LSD1 is a histone demethylase and a component of several histone deacetylase complexes. BHC110/LSD1 is able to specifically catalyze the demethylation of Lys4 of histone H3. As part of histone deacetylase complexes BHC110/LSD1 functions as a corepressor of transcription. BHC110/LSD1 has also been demonstrated to interact with the androgen receptor and stimulate androgen-receptor-dependent transcription.
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Gene ID
- 23028
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NCBI Accession
- NP_055828
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UniProt
- O60341
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Pathways
- Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Negative Regulation of intrinsic apoptotic Signaling, Warburg Effect
Target
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