EMSY antibody (C-Term)

Catalog No. ABIN7454601

This Rabbit Polyclonal antibody specifically detects EMSY in WB, IP and IHC (fp). It exhibits reactivity toward Human.

Quick Overview for EMSY antibody (C-Term) (ABIN7454601)

Target: EMSY (C11orf30) (Chromosome 11 Open Reading Frame 30 (C11orf30))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EMSY antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-EMSY Antibody

Binding Specificity: C-Term

Purpose: Rabbit anti-EMSY Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 1250 and C-term

Isotype: IgG

Application Details

Application Notes:

IHC: 1:500 to 1:2,000. Epitope retrieval with Tris-EDTA pH 9.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for EMSY

Target: EMSY (C11orf30) (Chromosome 11 Open Reading Frame 30 (C11orf30))

Alternative Name: EMSY

Background: Background: EMSY has been identified as a protein that interacts with BRCA2 and suppresses BRCA2 transactivational activity. EMSY is amplified in some cases of sporadic human breast and ovarian cancer indicating a role in tumorigenesis that is linked to BRCA2 function. EMSY can also associate with HP1beta and BS69 and may be involved in chromatin remodeling.

Gene ID: 56946

UniProt: Q7Z589, Q8TE50