BCL11B antibody (C-Term)

Catalog No. ABIN7454622

This Rabbit Polyclonal antibody specifically detects BCL11B in WB, IP and IHC (fp). It exhibits reactivity toward Human.

Quick Overview for BCL11B antibody (C-Term) (ABIN7454622)

Target: BCL11B (B-Cell CLL/lymphoma 11B (Zinc Finger Protein) (BCL11B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BCL11B antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-BCL11B Antibody

Binding Specificity: C-Term

Purpose: Rabbit anti-Bcl11b Antibody, Affinity Purified

Predicted Reactivity: Mouse

Purification: Affinity Purified

Immunogen: between AA 850 and C-term

Isotype: IgG

Application Details

Application Notes:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for BCL11B

Target: BCL11B (B-Cell CLL/lymphoma 11B (Zinc Finger Protein) (BCL11B))

Alternative Name: Bcl11b

Background: Background: Bcl11b is a zinc-finger transcription factor that is homologous to the proto-oncogene Bcl11a. Bcl11b functions in T-cell development, and as a tumor suppressor, plays a role in T-cell lymphoma pathogenesis. Bcl11b interacts with ARP1, SIRT1, and TFCOUP1 to modulate transcription.

Gene ID: 64919

NCBI Accession: NP_612808

UniProt: Q9C0K0