CCDC19 antibody (AA 501-551) (Biotin)

Catalog No. ABIN719143

This Rabbit Polyclonal antibody specifically detects CCDC19 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for CCDC19 antibody (AA 501-551) (Biotin) (ABIN719143)

Target: CCDC19 (Coiled-Coil Domain Containing 19 (CCDC19))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCDC19 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA

Product Details anti-CCDC19 Antibody (Biotin)

Binding Specificity: AA 501-551

Predicted Reactivity: Human,Mouse,Rat,Cow,Sheep,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CCDC19

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for CCDC19

Target: CCDC19 (Coiled-Coil Domain Containing 19 (CCDC19))

Alternative Name: CCDC19

Background:

Synonyms: Coiled coil domain containing 19, Nasopharyngeal epithelium specic protein 1, NESG1, RP11 190A12.6, CCD19_HUMAN.

Background: CCDC19 is a 466 amino acid protein encoded by a gene mapping to human chromosome 1. Chromosome 1 is the largest human chromosome, spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1 and, considering the great number of genes, there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes Lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinson?s, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.

Gene ID: 25790