PPP4C antibody (AA 1-50)

Catalog No. ABIN7454679

This Rabbit Polyclonal antibody specifically detects PPP4C in WB, IP and IHC (fp). It exhibits reactivity toward Human and Mouse.

Quick Overview for PPP4C antibody (AA 1-50) (ABIN7454679)

Target: PPP4C (Protein Phosphatase 4, Catalytic Subunit (PPP4C))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP4C antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-PPP4C Antibody

Binding Specificity: AA 1-50

Purpose: Rabbit anti-PPP4C Antibody, Affinity Purified

Predicted Reactivity: Rat,Bovine,Rabbit,Orangutan

Purification: Affinity Purified

Immunogen: between AA 1 and 50

Isotype: IgG

Application Details

Application Notes:

IHC: 1:200 - 1:1,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for PPP4C

Target: PPP4C (Protein Phosphatase 4, Catalytic Subunit (PPP4C))

Alternative Name: PPP4C

Background: Background: PPP4C, also known as PPX, is the catalytic subunit of the PP4 serine/threonine protein phosphatase. PP4 is a holoenzyme that is comprised of the PPP4C catalytic subunit in association with the PP4-R1 or PP4-R2 regulatory subunits. PP4 has been demonstrated to directly interact with and activate NF-kappaB. PP4 also has been demonstrated to interact with histone deacetylase HDAC3 to influence transcription and to serve a role in microtubule organization during mitosis. Signaling through the MAPK and JNK-1 pathway has also been demonstrated to involve PP4.

Gene ID: 5531

NCBI Accession: NP_002711

UniProt: P60510