SAFB2 antibody (AA 175-225)

Catalog No. ABIN7454719

The Rabbit Polyclonal anti-SAFB2 antibody has been validated for WB, IP and IHC (fp). It is suitable to detect SAFB2 in samples from Human.

Quick Overview for SAFB2 antibody (AA 175-225) (ABIN7454719)

Target: SAFB2 (Scaffold Attachment Factor B2 (SAFB2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SAFB2 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-SAFB2 Antibody

Binding Specificity: AA 175-225

Purpose: Rabbit anti-SAFB2 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 175 and 225

Isotype: IgG

Application Details

Application Notes:

IHC: 1:200 - 1:1,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for SAFB2

Target: SAFB2 (Scaffold Attachment Factor B2 (SAFB2))

Alternative Name: SAFB2

Background: Background: Scaffold attachment factor B2 (SAFB2) is a chromatin associated protein that interacts with DNA elements termed S/MARs (scaffold or matrix attachment regions) but is not part of the nuclear matrix. SAFB2 is structurally and functionally similar to SAFB1 and appears to be a multifunctional protein involved in chromatin organization, mRNA processing and transcriptional regulation. SAFB2 has been demonstrated to interact with and function as a corepressor with many nuclear receptors such as estrogen receptor-alpha, PPAR-gamma, and FXR-alpha.

Gene ID: 9667

NCBI Accession: NP_055464

UniProt: Q14151