GTF2I antibody (AA 935-985)

Catalog No. ABIN7454739

This Rabbit Polyclonal antibody specifically detects GTF2I in WB, IP and IHC (fp). It exhibits reactivity toward Human and Mouse.

Quick Overview for GTF2I antibody (AA 935-985) (ABIN7454739)

Target: GTF2I (General Transcription Factor III (GTF2I))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GTF2I antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-GTF2I Antibody

Binding Specificity: AA 935-985

Purpose: Rabbit anti-GTF2I/TFII-I Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 935 and 985

Isotype: IgG

Application Details

Application Notes:

IHC: 1:200 - 1:1,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for GTF2I

Target: GTF2I (General Transcription Factor III (GTF2I))

Alternative Name: GTF2I/TFII-I

Background: Background: GTF2I/TFII-I is a multi-functional transcription factor that interacts with the basal transcription machinery and links upstream cellular signals to responsive activator complexes that associate with the C-FOS promoter and other response elements. Haploinsufficiency of GTF2I/TFII-I results in Williams-Beuren syndrome (WBS), a rare developmental disorder characterized by musculo-skeletal and cardiac abnormalities.

Gene ID: 2969

NCBI Accession: NP_127492

UniProt: P78347