TNKS antibody (AA 1277-1327)

Catalog No. ABIN7454826

This Rabbit Polyclonal antibody specifically detects TNKS in WB, IP and IHC (fp). It exhibits reactivity toward Human.

Quick Overview for TNKS antibody (AA 1277-1327) (ABIN7454826)

Target: TNKS (Tankyrase, TRF1-Interacting Ankyrin-Related ADP-Ribose Polymerase (TNKS))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TNKS antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-TNKS Antibody

Binding Specificity: AA 1277-1327

Purpose: Rabbit anti-Tankyrase 1 Antibody, Affinity Purified

Predicted Reactivity: Mouse

Purification: Affinity Purified

Immunogen: between AA 1277 and 1327

Isotype: IgG

Application Details

Application Notes:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 5 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for TNKS

Target: TNKS (Tankyrase, TRF1-Interacting Ankyrin-Related ADP-Ribose Polymerase (TNKS))

Alternative Name: Tankyrase 1

Background: Background: Tankyrase-1 is a poly(ADP-ribose) polymerase that localizes to telomeres via its interaction with TRF1. Tankyrase modifies and associates with multiple proteins and appears to be involved in the maintenance of telomere length, sister telomere association, mitotic spindle organization, and trafficking of glut4-containing vesicles.

Gene ID: 8658

NCBI Accession: NP_003738

UniProt: O95271