IPO7 antibody (AA 50-100)

Catalog No. ABIN7454856

This Rabbit Polyclonal antibody specifically detects IPO7 in WB, IP and IHC (fp). It exhibits reactivity toward Human.

Quick Overview for IPO7 antibody (AA 50-100) (ABIN7454856)

Target: IPO7 (Importin 7 (IPO7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IPO7 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-IPO7 Antibody

Binding Specificity: AA 50-100

Purpose: Rabbit anti-Importin 7 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 50 and 100

Isotype: IgG

Application Details

Application Notes:

IHC: 1:200 - 1:1,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 5 - 15 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for IPO7

Target: IPO7 (Importin 7 (IPO7))

Alternative Name: Importin 7

Background: Background: Importin 7 autonomously mediates the nuclear import of ribosomal proteins RPL23A, RPS7 and RPL5. It binds to a beta-like import receptor binding (BIB) domain of RPL23A. In association with KPNB1 it mediates the nuclear import of H1 histone. In vitro, importin 7 mediates nuclear import of H2A, H2B, H3 and H4 histones. Also, in vitro, it mediates the nuclear import of HIV-1 reverse transcription complex (RTC) integrase and HIF-1 alpha [taken from the Universal Protein Resource (UniProt) ww.uniprot.org/uniprot/O95373].

Gene ID: 10527

NCBI Accession: NP_006382

UniProt: O95373

Pathways: Protein targeting to Nucleus