BIN1 antibody (AA 543-593)

Catalog No. ABIN7454858

This anti-BIN1 antibody is a Rabbit Polyclonal antibody detecting BIN1 in WB, IP and IHC (fp). Suitable for Human.

Quick Overview for BIN1 antibody (AA 543-593) (ABIN7454858)

Target: BIN1 (Bridging Integrator 1 (BIN1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BIN1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-BIN1 Antibody

Binding Specificity: AA 543-593

Purpose: Rabbit anti-Bin1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 543 and 593

Isotype: IgG

Application Details

Application Notes:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:500 - 1:2,500

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for BIN1

Target: BIN1 (Bridging Integrator 1 (BIN1))

Alternative Name: Bin1

Background: Background: Bin1 (bridging integrator 1) may be involved in the regulation of synaptic vesicle endocytosis. It may act as a tumor suppressor and inhibits malignant cell transformation. Defects in BIN1 are the cause of centronuclear myopathy autosomal recessive (ARCNM) [taken from the Universal Protein Resource (UniProt) ww.uniprot.org/uniprot/O00499].

Gene ID: 274

NCBI Accession: NP_647593

UniProt: O00499