FNBP1L antibody (AA 450-500)

Catalog No. ABIN7454919

This Rabbit Polyclonal antibody specifically detects FNBP1L in WB, IP and IHC (fp). It exhibits reactivity toward Human.

Quick Overview for FNBP1L antibody (AA 450-500) (ABIN7454919)

Target: FNBP1L (Formin Binding Protein 1-Like (FNBP1L))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FNBP1L antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-FNBP1L Antibody

Binding Specificity: AA 450-500

Purpose: Rabbit anti-Toca-1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 450 and 500

Isotype: IgG

Application Details

Application Notes:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for FNBP1L

Target: FNBP1L (Formin Binding Protein 1-Like (FNBP1L))

Alternative Name: Toca-1

Background: Background: Toca-1 is required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. Toca-1 may bind to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promote membrane invagination and the formation of tubules. Toca-1 also promotes CDC42-induced actin polymerization by activating the WASL/N-WASP-WASPIP/WIP complex, the predominant form of WASL/N-WASP in cells [taken from the Universal Protein Resource (UniProt) Q5T0N5].

Gene ID: 54874

NCBI Accession: NP_001157945

UniProt: Q5T0N5