26S Proteasome Regulatory Subunit 6A (PSMC3) (AA 339-389) antibody

Catalog No. ABIN7454925

This Rabbit Polyclonal antibody specifically detects 26S Proteasome Regulatory Subunit 6A in IHC (fp), IP and WB. It exhibits reactivity toward Human and Mouse.

Quick Overview for 26S Proteasome Regulatory Subunit 6A (PSMC3) (AA 339-389) antibody (ABIN7454925)

Target: 26S Proteasome Regulatory Subunit 6A (PSMC3)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)), Immunoprecipitation (IP), Western Blotting (WB)

Product Details

Binding Specificity: AA 339-389

Purpose: Rabbit anti-TBP1 Antibody, Affinity Purified

Predicted Reactivity: Rat,X. laevis

Purification: Affinity Purified

Immunogen: between AA 339 and 389

Isotype: IgG

Application Details

Application Notes:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details

Target: 26S Proteasome Regulatory Subunit 6A (PSMC3)

Alternative Name: TBP1

Background: Background: Tat-binding protein 1 (TBP1) is a regulatory subunit (subunit 6A) of the 26S protease involved in the ATP-dependent degradation of ubiquitinated proteins. This subunit may compete with PSMC2 for binding to the HIV tat protein to regulate the interaction between the viral protein and the transcription complex.

Gene ID: 5702

NCBI Accession: NP_002795

UniProt: P17980