RING1 antibody (AA 150-200)

Catalog No. ABIN7454929

The Rabbit Polyclonal anti-RING1 antibody has been validated for WB, IP and IHC (fp). It is suitable to detect RING1 in samples from Human.

Quick Overview for RING1 antibody (AA 150-200) (ABIN7454929)

Target: RING1 (Ring Finger Protein 1 (RING1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RING1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-RING1 Antibody

Binding Specificity: AA 150-200

Purpose: Rabbit anti-RING1 Antibody, Affinity Purified

Predicted Reactivity: Monkey,Gorilla,Chimpanzee

Purification: Affinity Purified

Immunogen: between AA 150 and 200

Isotype: IgG

Application Details

Application Notes:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for RING1

Target: RING1 (Ring Finger Protein 1 (RING1))

Alternative Name: RING1

Background: Background: Ring finger protein 1 (RING1) belongs to the RING finger family, members of which encode proteins characterized by a RING domain, a zinc-binding motif related to the zinc finger domain. RING1 can bind DNA and can act as a transcriptional repressor. It is associated with the multimeric polycomb group protein complex. RING1 interacts with the polycomb group proteins BMI1, EDR1, and CBX4, and colocalizes with these proteins in large nuclear domains. It also interacts with the CBX4 protein via its glycine-rich C-terminal domain [taken from NCBI Entrez Gene (Gene ID: 6015)].

Gene ID: 6015

NCBI Accession: NP_002922

UniProt: Q06587