ETV6 antibody (AA 175-225)

Catalog No. ABIN7454944

The Rabbit Polyclonal anti-ETV6 antibody has been validated for WB, IP and IHC (fp). It is suitable to detect ETV6 in samples from Human.

Quick Overview for ETV6 antibody (AA 175-225) (ABIN7454944)

Target: ETV6 (Ets Variant 6 (ETV6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ETV6 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-ETV6 Antibody

Binding Specificity: AA 175-225

Purpose: Rabbit anti-ETV6 Antibody, Affinity Purified

Predicted Reactivity: Bovine

Purification: Affinity Purified

Immunogen: Between AA 175 and 225

Isotype: IgG

Application Details

Application Notes:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:1,000 - 1:5,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for ETV6

Target: ETV6 (Ets Variant 6 (ETV6))

Alternative Name: ETV6

Background: Background: ETS translocation variant 6 (ETV6) functions as a transcriptional repressor. Gene knockout studies in mice suggest that ETV6 is required for hematopoiesis and maintenance of the developing vascular network. The ETV6 gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma [taken from NCBI Entrez Gene (Gene ID: 2120)].

Gene ID: 2120

NCBI Accession: NP_001978

UniProt: P41212