SAMHD1 antibody (AA 576-626)

Catalog No. ABIN7454949

This Rabbit Polyclonal antibody specifically detects SAMHD1 in WB, IP and IHC (fp). It exhibits reactivity toward Human.

Quick Overview for SAMHD1 antibody (AA 576-626) (ABIN7454949)

Target: SAMHD1 (SAM Domain and HD Domain 1 (SAMHD1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SAMHD1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-SAMHD1 Antibody

Binding Specificity: AA 576-626

Purpose: Rabbit anti-SAMHD1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 576 and 626

Isotype: IgG

Application Details

Application Notes:

IHC: 1:500 - 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for SAMHD1

Target: SAMHD1 (SAM Domain and HD Domain 1 (SAMHD1))

Alternative Name: SAMHD1

Background: Background: SAM domain and HD domain-containing protein 1 (SAMHD1) is a putative nuclease involved in innate immune response by acting as a negative regulator of the cell-intrinsic antiviral response. SAMHD1 may play a role in mediating proinflammatory responses to TNF-alpha signaling [taken from the Universal Protein Resource (UniProt) Q9Y3Z3].

Gene ID: 25939

NCBI Accession: NP_056289

UniProt: Q9Y3Z3