JAM3 antibody (AA 260-310)

Catalog No. ABIN7454958

This Rabbit Polyclonal antibody specifically detects JAM3 in WB, IP and IHC (fp). It exhibits reactivity toward Human.

Quick Overview for JAM3 antibody (AA 260-310) (ABIN7454958)

Target: JAM3 (Junctional Adhesion Molecule 3 (JAM3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This JAM3 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-JAM3 Antibody

Binding Specificity: AA 260-310

Purpose: Rabbit anti-JAM-C Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 260 and 310

Isotype: IgG

Application Details

Application Notes:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for JAM3

Target: JAM3 (Junctional Adhesion Molecule 3 (JAM3))

Alternative Name: JAM-C

Background: Background: Junctional adhesion molecule C (JAM-C) participates in cell-cell adhesion. JAM-C is a counter-receptor for ITGAM, mediating leukocyte-platelet interactions and is involved in the regulation of transepithelial migration of polymorphonuclear neutrophils (PMN). The soluble form of JAM-C is a mediator of angiogenesis [taken from the Universal Protein Resource (UniProt) Q9BX67].

Gene ID: 83700

NCBI Accession: NP_116190

UniProt: Q9BX67