SFRS7 antibody (AA 188-238)

Catalog No. ABIN7454960

This anti-SFRS7 antibody is a Rabbit Polyclonal antibody detecting SFRS7 in WB, IHC (fp) and IP. Suitable for Human and Mouse.

Quick Overview for SFRS7 antibody (AA 188-238) (ABIN7454960)

Target: SFRS7 (Splicing Factor, Arginine/Serine Rich 7 (SFRS7))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SFRS7 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)), Immunoprecipitation (IP)

Product Details anti-SFRS7 Antibody

Binding Specificity: AA 188-238

Purpose: Rabbit anti-SRSF7 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 188 and 238

Isotype: IgG

Application Details

Application Notes:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 or Tris-EDTA pH 9.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for SFRS7

Target: SFRS7 (Splicing Factor, Arginine/Serine Rich 7 (SFRS7))

Alternative Name: SRSF7

Background: Background: Serine/arginine-rich splicing factor 7 (SRSF7) is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation [taken from NCBI Entrez Gene (Gene ID: 6432)].

Gene ID: 6432

NCBI Accession: NP_001026854

UniProt: Q16629